Contains per g:
Gentamycin sulphate 200 mg
Doxycycline hyclate 200 mg
Doxy-Gen 20/20 wsp is a combination preparation containing gentamycin and doxycycline and provides a broad antibacterial spectrum covering the most microbial agents producing diseases in animals. Gentamycin belongs to the group of amino-glycoside antibiotics and has bactericidal action. It has a broad antibacterial spectrum and is active against Gram-positive and Gram-negative bacteria (including Pseudomonas spp., Klebsiella spp., Enterobacter spp., Serratia spp., E. coli, Proteus spp., Salmonella spp., staphylococci). Moreover, it is active against Campylobacter fetus subsp. jejuni and Treponema hyodysenteriae. Gentamycin may be active against bacteria which are resistant to other amino-glycoside antibiotics (like Neomycin, Streptomycin, Kanamycin).
Doxycycline is a tetracycline antibiotic with bacteriostatic action against a large number of Gram-positive and Gram-negative bacteria (like Staphylococcus spp., Haemophilus influenza, E. coli, Corynebacteria, Bacillus anthracis, some Clostridium spp., Actinomyces spp., Brucella spp., Enterobacter spp., Salmonella spp., Shigella spp. and Yersinia spp.). It also acts against Mycoplasma spp., Rickettsiae and Chlamydia spp. Gentamycin is not absorbed from the gastrointestinal tract and therefore acts locally. Following oral administration, doxycycline is rapidly absorbed from the gastrointestinal tract and produces a therapeutic blood level quickly, which persists for a long period, as doxycycline has a relatively long-serum half-life. Doxycycline has a great affinity to lung tissues, therefore it is recommended especially for respiratory tract infections. This combination provides an intensive antibacterial effect in the gastrointestinal tract and a rapid and intensive systemic effect after absorption. Doxy-Gen 20/20 wsp is a potent antibacterial product and useful in most infective diseases in the targeted animals.
Doxy-Gen 20/20 wsp is indicated for the treatment of infections caused by micro-organisms susceptible to gentamycin and/or doxycycline. The product is used especially with gastrointestinal infections in calves and poultry and infections of the respiratory tract in poultry, calves and pigs.
Do not administer to animals hypersensitive to amino-glycosides and/or tetracyclines. Do not use in animals with an impaired kidney function, vestibular and/or ear dysfunctions, impaired eye function or an impaired liver function. Do not use in animals in lactation if milk is intended for human consumption.
Kidney damage and/or ototoxicity, hypersensitivity reactions like gastrointestinal disturbances or changes of intestinal flora.
INCOMPATIBILITY WITH OTHER DRUGS:
Do not combine with potential nephrotoxic or muscle paralysing medicines.
DOSAGE AND ADMINISTRATION:
For oral administration via feed or drinking water.
- Poultry: 100 g per 300 litres of drinking water during 3 – 5 days.
- Calves: 100 g per 60 calves of 50 kg bodyweight during 4 – 6 days.
- Pigs: 100 g per 200 litres of drinking water during 4 – 6 days.
Mixed with feed the product should be used immediately. Medicated drinking water should be used within 24 hours.
- Cattle: 90 days
- Pigs: 40 days
Eggs: 14 days